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These usually resolve by lowering frequency or concentration

Between 13 months , most patients experience substantial improvement in both haematological and non-neurological symptoms

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Microglial and astrocytic proteins are preferentially elevated in the GCLC-KO mouse brain To uncover mechanisms leading to brain atrophy in GCLC-KO mice, we next performed a comprehensive analysis of protein expression by Liquid Chromatography-Mass spectrometry (LCMS) analysis using brain samples from 4-month-old GCLC-KO mice (Fig

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doi: 10.1038/s41574-023-00858-9 18 UssherJRDruckerDJ