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Embora esses estudos sejam publicados em revistas indexadas, a replicao independente por outros grupos de pesquisa permanece insuficiente para tirar concluses definitivas sobre a eficcia teraputica em humanos

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The Authors reported that treatment with incretins significantly suppressed the FSH-induced synthesis of progesterone through the inhibition of the expression of progestogenic factors and enzymes, whereas there was no significant effect on oestrogen synthesis by rat granulosa cells, thus suggesting the possible role of GLP-1 RA in the treatment of dysregulated steroidogenesis in PCOS [43]

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& Goodpasture, J