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GLP-1 receptor agonists like semaglutide (Wegovy) and tirzepatide (Zepbound) have emerged as powerful tools for chronic weight management, but their use in patients with underactive thyroid requires careful medical evaluation
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Dose: 1000 IU or less for women and between 2000-4000 IU for men could be recommended
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In these cases, IV delivery is the most practical route for reaching therapeutic plasma concentrations quickly
Generally, clinical studies have been known to show that treatment with tirzepatide over a 52-week period led to large amounts of weight loss in comparison to a placebo
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