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1,3 Risk factors Factors which increase the risk of melanoma include: 2 History of skin cancer, melanoma or atypical naevi Family history of melanoma Pale skin (Fitzpatrick skin type I and II) Red or light-coloured hair High freckle density Light-coloured eyes History of sunburn High sun exposure or tanning bed exposure Large numbers of moles Increasing age Immunosuppression Outdoor occupation Genetic syndromes with skin cancer predisposition (for example, xeroderma pigmentosum) Clinical features The first sign of melanoma is often a change in a previous mole or freckle, or a new lesion arising in previously normal skin

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Srivastava S, Srivastava AK, Suprasanna P, DSouza SF (2010) Comparative antioxidant profiling of tolerant and sensitive varieties of Brassica juncea L

In a meta-analysis, vitamin D deficiency is a risk factor for TC [208]

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