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10.1016/j.cmet.2013.04.008 67

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Ice Cream: How to Fit It In Mass General Brigham suggests eating sweets with your meal, instead of separately

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Therapeutically, phenotype-specific strategiessuch as NAD + repletion, SIRT activation, BCAA catabolism modulation, and ferroptosis inhibitionare emerging but require biomarker-guided trials

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Similar outcomes were observed with Wegovy, where 1.6% of users developed gallstones, compared to 0.7% in the placebo group

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This suggests that any initial fatigue is typically outweighed by the positive effects of weight loss and improved metabolic health over time

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Regular physical activity, such as aerobic exercise and strength training, can help increase energy expenditure and promote fat loss

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