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Medical News Today, 2024
The Ph.D
[84] [85] The 5-reductase inhibitors are contraindicated in pregnant women because of their teratogenicity due to interference with fetal testosterone metabolism, and as a precaution, pregnant women should not handle crushed or broken tablets
Never shake the vial or spray water directly on the powder
Analytical Method & Instrumentation Method:ICP-MS per ICH Q3D(R2) / USP / ChP 0412 Instrument:Agilent 7900 ICP-MS (SN: JP55795) with He collision mode Sample Prep:Closed-vessel microwave digestion (CEM MARS 6): 32.5 mg + 5mL HNO(suprapure) + 1mL HO (30%) Digestion:Ramp 20min 200C, hold 15min, cool to RT, dilute to 50.0 mL (Milli-Q, 18.2 Mcm) Calibration:Multi-element std (NIST SRM 3100 series), 5-point external cal
The solution should be perfectly clear and free of any particulate matter, cloudiness, or color changes
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