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This trend also underscores the likely spillover that occurred for Ozempic as heightened patient demand for Wegovy and Mounjaro encountered access and supply challenges

GLP-1 receptors are activated by mimicking the endogenous GLP-1 to enhance insulin secretion and inhibit glucagon secretion in a glucose-dependent manner, as well as delay gastric emptying and reduce food intake through the suppression of appetite, thereby reducing blood sugar

5 A large body of data indicate that GLP-1 has an important role in satiation signaling, but this does not appear to be the case for GIP

Overall, GLP-1RAs is a relatively safe and effective new hypoglycemic drug, which helps to delay the occurrence and development of diabetes

Patients currently using compounded semaglutide should discuss transitioning to FDA-approved alternatives with their healthcare provider

The second eye is affected in roughly 15 to 25% of cases over five years