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Both produce substantial fat loss, but the proportional effects on muscle and other lean tissues differ in ways that matter for long-term metabolic health and physical function

Insulinotropin: Glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas

Reid M et al

For many patients, this includes GLP-1 medications such as semaglutide and tirzepatide, which help regulate appetite, support metabolic function, and encourage steady weight loss