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Myth: "All antioxidants do the same thing, so you only need one." Fact: Antioxidants are specialized

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Research utilizing the Broad Institute's Connectivity Map indicates it influences the expression of over 4,000 genes (~31% of the human genome), shifting gene signatures from a pathological state back to a healthier, regenerative baseline

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Indications: FDA : Topical anesthesia of the upper respiratory tract (due to its combined vasoconstrictor & local anesthetic properties) Off Label : Use in Emergency Department as one ingredient in a topical anesthetic solution called TAC (containing: Tetracaine, Adrenaline & Cocaine) that is applied to a wound prior to cleaning & suturing Contraindications: Hypersensitivity to ester anesthetics Side Effects: Acute signs of systemic toxicity include can include multiple signs of both CV & CNS stimulation: tachycardia hypertension hyperthermia mydriasis seizures cardiac arrhythmias (multiple contributing variables: Na & K channel block, possible coronary vasoconstriction) Acute effects associated with cocaine abuse

PMID 38189492