It is worth noting that chlorophytes but not terrestrial plants contain Tyr-GST isoforms (respectively, 6, 4, and 7 in Chlamydomonas reinhardtii, Micromonas pusilla , and Volvox carteri ) also shared by animals
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and actually SARS-CoV-2 causing COVID-19, all are characterized by persistent inflammation, continuous production of reactive oxygen/nitrogen species and oxidative stress that predominate over the antioxidant defenses (GSH and free radical scavenger enzymes) resulting in cell/tissue/organ aging associated with early (premature) chronic inflammation/inflammaging. We propose that, although inflammaging was introduced for the aging process (276289), it could also apply to early (premature) tissue and organ aging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses, especially low GSH levels, in younger individuals
PSM in the news PSM was cited throughout national coverage of the FDA's PCAC meeting
in the second half of 2024