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When tirzepatide binds to these receptors, it enhances glucose-dependent insulin secretion from pancreatic beta cells, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying

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[1] [3] Marketed under the brand names Mounjaro (for diabetes) and Zepbound (for weight management), tirzepatide represents the first dual incretin receptor agonist available in clinical practice

The PHQ-9: a new depression diagnostic and severity measure