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Mechanism: Berberine activates the AMPK metabolic master pathway, improves insulin sensitivity, suppresses hepatic glucose production, and promotes fatty acid oxidation

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Semaglutide, a GLP-1 receptor agonist marketed as Ozempic, Wegovy, and Rybelsus, has gained widespread attention for its effectiveness in managing type 2 diabetes and promoting weight loss

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Mild means occasional nausea that doesn't interfere with daily activities, manageable constipation, or transient fatigue

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