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The upregulation of miR-195 in the diabetic rat retina decreased mitofusin 2 (MFN2) protein levels, reduced mitochondrial fusion, accelerated oxidative stress-induced damage to RECs in diabetic rats, and increased diabetic retinal vascular permeability [84]

An analysis of four clinical trials that evaluated an erythropoiesis-stimulating agent known as darbepoetin alfa (Aranesp) found that it increased hemoglobin levels and improved chemotherapy-induced fatigue (Revicki 2012)

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