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OBESITY EXPERT REVEALS THE BEST WAY TO DECIDE IF GLP-1S ARE RIGHT FOR YOU The New England Journal of Medicine published results from a 2023 phase 2 retatrutide trial for obesity, revealing "substantial reductions in body weight" after 48 weeks of treatment
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10.2337/db13-1169 26 Nuche-BerenguerB.MorenoP.EsbritP.DapaS.CaeiroJ
on August 18, 2025 The FDA has granted accelerated approval of semaglutide 2.4 mg for the treatment of metabolic dysfunction-associated steatohepatitis (MASH) in adults with moderate to advanced liver fibrosis
But as the lengthy history shows from the Gila monster discovery in the early 1990s to FDA approvals spanning nearly two decades these medications have been rigorously researched
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