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Interestingly, after Semaglutide intervention, ABHD6 expression was significantly decreased in the liver of T2DM+NAFLD mice and in HG+FFA-stimulated Hepa 1-6 hepatocytes, while miR-5120 expression was increased
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The single biggest theoretical objection to adding glucagon to an obesity drug is that it could worsen glucose control a serious problem in a population where prediabetes and diabetes are common
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