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doi: 10.3389/fnmol.2017.00033 Received 29 September 2016 Accepted 27 January 2017 Published 13 February 2017 Volume 10 - 2017 Edited by Ildik Rcz, University of Bonn, Germany Reviewed by Wei Chen, Beijing Institute of Pharmacology and Toxicology, China
Launched by Eli Lilly in late 2023, Zepbound combines GLP-1 and GIP receptor agonism to deliver superior weight loss compared to single agonists
In doing so, the permeation enhancing capabilities would be retained, as the organic moiety is responsible for interacting with the epithelial membrane, while the cation would affect the physical form of the salt, leading to a liquid state which would enable high concentrations of PE per dosage unit
Conversely, if tirzepatide worked well, understanding your GIPR predisposition may explain why the dual mechanism benefited you specifically
It is a GLP-1 and GIP receptor agonist
