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The follow-up 2023 systematic review by the same team covered 33 studies and 1,180 participants across 23 different growth factor preparations and concluded that topical growth factor application is effective for facial skin rejuvenation, particularly when delivery is enhanced [6]

Topical medications are usually effective for managing mild-to-moderate cases

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This results in the acceleration of cell renewal/turnover

Older adults managing age-related decline Aging brings slower healing, increased injury susceptibility, and accumulated damage from decades of activity

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