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PLoS ONE 9(8):e103929 Burstein R, Jakubowski M, Garcia-Nicas E et al (2010) Thalamic sensitization transforms localized pain into widespread allodynia

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In brief, it is suggested that an elevated secretion of pro-inflammatory cytokines and diminished hepatoprotection by IL-6 might contribute to TVX-induced hepatotoxicity in the model, whereas the non-DILI reference drug LVX did not alter the cytokine profiles