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Never add water to a still-frozen peptide
However, you should always inform your prescribing clinician about all supplements you are taking to ensure personalised advice based on your individual health status
The answer is bioavailability
Shaking creates bubbles, denatures the peptide, and gives you inaccurate draws because air pockets displace liquid in the syringe
Most potential products tested in rodents do not make it to market
Most side effects lessen over time
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