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Device: Oral tablet (R1 formulation

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Discussion Our data suggests that physiological (picomolar) concentrations of GLP-1 exert their glucagonostatic effects via mechanisms that are (at least in part) intrinsic to the glucagon-secreting -cells and that are independent of paracrine effects from the neighboring islet cells

The typical outcome measure used by researchers is the Sciatic Function Index that assesses hind limb motor function based on toe to toe and toe to heel distance

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