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World obesity atlas 2024
and Doll et al
High potency can lead to dangerous drops in blood sugar
338,339 Additionally, NPR1 signaling exerts pleiotropic cardiorenal benefits, 339,340 including natriuresis, diuresis, and vasorelaxation
For patients with an A1C of 6.5% to 7.5%, metformin is the preferred initial agent, with GLP-1 receptor agonists, dipeptidyl-peptidase-4 (DPP-4) inhibitors, thiazolidinediones (TZDs), or an alpha-glucosidase inhibitor listed as viable alternatives
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