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Ceramides (1, 3, 6-II): Essential for rebuilding the stratum corneum and locking in moisture

Two review articles by Graf and colleagues compiled the early body of work (PMID 6145137, PMID 3550726)

Why It Matters: Certain combinations may compete for absorption, create conflicting metabolic signals, or produce unwanted interactions

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For context, that level of glycemic control often allows patients to reduce or eliminate other diabetes medications