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Glucose-stimulated insulin secretion in pooled islets isolated from 1015-wk old male (n = 9) and female (n = 6) C57BL6/J mice treated with either control, GLP-1RA or GLP-1RA + Tesaglitazar (n = 9/6/6 biologically independent biological replicates) (e) or with control or GLP-1RA/Tesaglitazar (n = 9/6 independent biological replicates) (f) under dynamic glucose concentrations ranging from 2.716 mM at drug concentrations of 3 nM

E.FeiziF.WuC.ZhangY.YangM

These findings suggest oral administration can be effective, at least in rodent models

Change of antioxidant enzyme activities, some metals and lipid peroxidation in Alzheimer's disease

References Noctor, G

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