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Originally developed to treat type 2 diabetes, semaglutide is now FDA-approved for weight management and has shown impressive results in clinical trials

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Meet our doctors Last reviewed: 19 Jun 2026 Sources Glucagon-like peptide-1 (GLP-1): a gut hormone of potential interest in the treatment of diabetes (1998) PubMed [accessed 21 October 2025] Wegovy dosing schedule (2024) Wegovy.com [accessed 21 October 2025] Wegovy (semaglutide): a new weight loss drug for chronic weight management (2022) BMJ [accessed 21 October 2025] Wegovy 0.25 mg, FlexTouch solution for injection in pre-filled pen (2023) EMC [accessed 13 January 2026] Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes, The New England Journal of Medicine [accessed 21 October 2025] Weight loss injections NHS weight loss injections GLP-1 for weight loss Can doctors help with weight loss

Highlights of Prescribing Information: Contrave (naltrexone hydrochloride and bupropion hydrochloride) extended-release tablets, for oral use

Consult a health care practitioner before using this product if: you are pregnant or breastfeeding, you are taking lithium or have a seizure disorder