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(2) major adverse cardiovascular events (MACE)

Experimental design All animals were divided into seven groups via randomization, viz., Sham ( n = 25), Stroke ( n = 35), CKD ( n = 22), CKD + Stroke ( n = 40), Stroke + 4PBA ( n = 29), CKD + 4PBA ( n = 25), CKD + Stroke + 4PBA ( n = 30)

This study was supported by the Shandong University of Traditional Chinese Medicine Doctoral Student Quality Improvement Innovation Project (YJSTZCX2024018), the Inheritance Studio of Traditional Chinese Medicine Master Zhang Canjia of State Administration of Traditional Chinese Medicine (no.(2010) 59), the Chinese Medicine Science and Technology Project of Shandong Province in 2023 (M-2023031), and the Key Project of Undergraduate Teaching Reform Research in Shandong Province (Z2023292)

Administration frequency can differ among GLP-1 medications: Liraglutide : Usually administered daily

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