$10 million payment for completion of the first technical milestone represents the first of these payments
Simon, Glutathione metabolism in cancer progression and treatment resistance
The main practical disadvantages are: poor absorption in standard capsule form, the need for consistent daily use over 8-12+ weeks before visible results, relatively higher cost for well-absorbed formats, mild and uncommon side effects like digestive discomfort or headache in some users, and the risk of unrealistic expectations from aggressive marketing claims
A post hoc sensitivity analysis (two-sided, = 0.05) indicated that the n = 6 per group design has adequate power to detect large effects (standardized mean difference ~ 1.4), whereas smaller effects may be underpowered
E.et al (2013)
Although AtGrxS15 catalysis was less efficient than for the dithiol glutaredoxin AtGrxC1, the oxidation of roGFP2 clearly depended on the concentration of AtGrxS15