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Licensed medicines undergo rigorous clinical testing and are prescribed with medical supervision, making interactions with levothyroxine easier to monitor and manage
The short answer is that whilst there is no absolute contraindication, combining berberine with metformin requires careful medical supervision due to overlapping mechanisms of action and the potential for additive effects on blood glucose levels
Creatine is better suited for strength and muscle growth, while L-Carnitine supports endurance and fat oxidation
However, research specifically on IGF-1 LR3 remains limited, and there is currently insufficient clinical evidence to conclude that it safely or effectively supports tendon or ligament healing in humans