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But it came with what researchers call "retinoid dermatitis": inflammation mediated by MCP-1 and IL-8 cytokine release, barrier disruption from transepidermal water loss, and photosensitivity from exposing fresh, immature cells to UV

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Preparation records should include product name, lot number, solvent, target concentration, date prepared, storage temperature, operator initials, and intended assay

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Both legal authorities and medical ethics counsel restraint