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Extensive anaerobic subculturing of human feces identified no single commensal capable of l-carnitineTMA transformation, multiple community members that converted l-carnitine to BB, and only 1 Clostridiales bacterium, Emergencia timonensis, that converted BB to TMA

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This includes investigating its potential in treating specific diseases

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However, as human erythrocytes are nucleus- and organelle-free cells, the effects of erythrocytic ceramides should be restricted to the plasma membrane and plasma membrane-associated proteins

Replacement of Lys105 by uncharged residues in K105A/Y resulted in a 6597% decrease of the k cat app values for GSSCys and GSH (Fig