Few, if any, large, randomized clinical trials exist for these supplements specifically targeting GLP-1 in humans
The SURMOUNT-OSA trials revealed that Tirzepatide dramatically reduced obstructive sleep apnea severity by finding that the drug decreased case patients' apnea-hypopnea index (AHI), a measure of breathing interruptions, by an estimated 2024 events per hour more than controls, depending on whether patients were using positive airway pressure (PAP) therapy at baseline
Nicholls DG, Locke RM
What Research Says The concern about creatine damaging kidneys persists online despite decades of evidence showing otherwise
It was then discovered that GLP-1 is rapidly degraded by the enzyme DPP4, giving rise to the development of GLP-1 receptor agonists (RAs) and DPP4 inhibitors for the treatment of type 2 diabetes (T2D), and GLP-1 RAs for the treatment of obesity
Tell your provider if you have a history of pancreatitis, diabetic retinopathy (vision changes), hypoglycemia (low blood sugar), kidney problems, gallbladder disease, or an allergy to any active ingredients in the tirzepatide or semaglutide product