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So far, oral GLP-1 therapies have been developed to reduce patient reliance on injections

Others have demonstrated that the positive outcomes of obesity surgery (i.e., changes in body weight and improved glucose homeostasis) are sustained in mice in the absence of GLP-1R or Y2-R, or both GLP-1R and Y2-R 66,67

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We compared logistic regression, LightGBM, artificial neural networks (ANNs), and support vector classifier (SVC), to identify the best model for predicting GLP-1 M responsiveness

The drug may still offer important systemic benefits