Side effects include flushing, chest tightness or pressure, headache, weakness, and flu like symptoms that can last a few minutes
These effects, when present, are typically manageable and resolve with continued use or dose adjustment
But whether boosting NAD+ in the body has clinical effectiveness for anti-aging or wellness is inconclusive, according to the latest review of evidence by the Ageing Research Reviews journal
B12 is one of the most common vitamin deficiencies
If you increase your dose to get results, you are also increasing your exposure to potentially impure substances
Clinical trials tested doses up to 1mg daily without significant adverse effects, but this does not mean higher doses produce better results or that exceeding researched doses is safe