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However, the authors urge caution in interpreting these findings due to the limited number of trials, the variations in study designs, and the heterogeneity in patient populations and substance types studied

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Even safety data on TB-500 (synthetic TB4) is relatively scarce, with only a few studies reporting the potential side effects of its systemic application: In a 2010 study in 10 participants, TB4 caused occasional mild to moderate symptoms like headache and dizziness but no serious reactions or toxicities, even at doses up to 1260mg, administered daily for up to two weeks

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Whilst current evidence does not support a link between Wegovy and blood clots, continued post-marketing surveillance remains important for detecting rare or delayed adverse effects