Current safety data support long-term use with appropriate monitoring
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Waist circumference often drops faster than scale weight during early treatment
This supports skin barrier function, too
Owing to donor-to-donor variability associated with human samples, we repeated this protocol in additional sets of islets from humans that spanned a range of BMI, age and HbA1C%, and included donors of both sexes (Extended Data Table 2)
When the body is dehydrated, blood volume decreases, which can cause a drop in blood pressure and result in feelings of dizziness or even fainting