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A large cardiovascular outcomes trial found that higher proportions of tirzepatide recipients reported vomiting, diarrhea, and nausea compared to those taking a selective GLP-1RA
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A favorable effect was noticed on the level of IL-6 and IGF-1, but this effect did not reach a significant level
PKA induction from native GLP-1 phosphorylates a key serine residue in NOS [40]
Other possible ipamorelin side effects There is currently no data from clinical trials linking ipamorelin to major side effects in humans
