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The rate-limiting step in its de novo biosynthesis is the enzyme glutamate-cysteine ligase (GCL)

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In some people, it can affect the tissues around the eyes, certain nerves, the meninges (the protective layers around the brain), or glands in the face and neck and that can lead to headaches, swelling, or eye problems

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Blood was collected by cardiac puncture for biochemical measurements

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Aggregated across hundreds of thousands of posts, those descriptions can surface patterns that formal trial structures might miss

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