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21 Although the mechanisms underlying the cardiovascular benefits of GLP-1R agonists are still being elucidated, it is reasonable to conclude that some of these benefits are dependent on absolute weight loss
But do weight loss drugs really work
During follow-up, modest increases in amylase and lipase levels were observed, with higher values detected in the dulaglutide group at 3 and 6 months
Researchers note that more work is needed to determine if these organ changes also occur in humans and whether they carry any health risks
The key results: 13.6% average weight loss with oral semaglutide, compared to 2.2% with placebo 76.3% of people on the pill achieved at least 5% weight loss, compared to 31.3% on placebo 55.6% achieved at least 10% weight loss Around 30% achieved 20% or more weight loss Theres an important distinction in how these results are reported
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