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(a ) GIPR IC 50 and GLP-1R EC 50 are comparable with both molecules, despite different GLP-1 analogs used

Oxidation occurs even at refrigerated temperatures but accelerates exponentially as temperature rises

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Therefore, we highlight pharmacological approaches for MASLD that are weight-neutral or associated with weight reduction or weight gain (mostly an increase in subcutaneous adipose tissue) (see Text box, Summary of pharmacological treatment of MASH in people with type 2 diabetes)