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Insulin-like growth factor-I and neurogenesis in the adult mammalian brain
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10.1016/S2215-0366(17)30015-9 63
Among the tissues and organs crucial in regulating glucose and lipid metabolism, pancreas, brain, and adipocytes express GIP receptors (GIPRs), while pancreas, brain, and gastrointestinal tract are rich in GLP-1 receptors (GLP-1Rs) (40)
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They were originally developed to treat type 2 diabetes but have since become one of the most significant advances in obesity medicine
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