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Summarizing the risk associated with LC supplementation Hathcock and Shao [89] indicated that intakes up to 2 g/day are safe for chronic supplementation

Prohaska JR et al

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In addition, activation of this pathway suppresses NOD-like receptor protein 3 (NLRP3) inflammasome activity, reducing the maturation and release of proinflammatory cytokines such as interleukin-1 (IL-1)

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