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Leptin action in the brain potently suppresses hepatic glucose production while increasing tissue glucose uptake despite persistent, severe insulin deficiency (German et al., 2011)
And as weve discussed, glutathione deficiency can lead to oxidative stress
Since BAT has the function of thermogenesis and heat generation, promoting TG clearance and glucose metabolism
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doi: 10.1210/jcem.81.3.8772550 97 LeeJHFangCLiXWuCSNohJYYeXet al
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