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Medical legitimacy: In 2026 this matters more than ever
The p53(3KR) mutant, lacking acetylation due to lysine-to-arginine substitutions at three residues, decreases expression of SLC7A11 without affecting other p53 targets such as CDKN1A/p21 (involved in cell cycle progression) or BAX (involved in apoptosis)
Increased cellular turnover contributes to a more youthful appearance
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The researchers didnt dive into this question in their research, but experts have some theories
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