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In animal models finerenone reduced the expression of genes encoding monocyte chemoattractant protein-1, matrix metalloproteinase-2 and plasminogen activator inhibitor-1 (related to tissue remodelling and fibrosis) in the kidney, and additionally demonstrated beneficial immunomodulatory effects [73]
doi: 10.1136/bmj.m3773 22 VuongNHSalah SalahOVanderhydenBC
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Meanwhile, the peptide mice exhibited a decrease in the number of tumor cells
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