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For individuals with established cardiovascular disease, beta blockers are often a cornerstone of treatment, particularly following a heart attack or in heart failure with reduced ejection fraction

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Each session involved testing only one hind paw at a time, with a maximum duration of 20 s for each immersion to safeguard the animal's well-being

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Ipamorelin is supplied as a white to off-white lyophilised solid for reconstitution at the bench with a research solvent such as bacteriostatic water