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Furchgott RF, Zawadzki JV (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

The optimum time to induce ECD by starvation was 96 h since a decrease in angiogenic and migratory capabilities, as well as an increase in recognized markers of senescence, such as -galactosidase, were observed [116]

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Obesity and metabolic syndrome are associated with lower GSH-to-GSSG ratios indicating oxidative stress but this reflects increased demand rather than absolute deficiency