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A mannosyltransferase PMT4 mutant also displayed reduced conidiation, however a deletion mutant of PMT2 was not viable suggesting the gene is essential 38
TPE is an archetypal AIE fluorogen which is easy to synthesize and ready to functionalize 41
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If a patient is still on 0.5 or 1 mg weekly semaglutide and has hit a stall, moving to 1.7 or 2.4 mg often resolves it without adding another compound
A 2025 paper in Biogerontology characterised that epitalon increased telomere length in human cell lines through upregulation of the telomerase enzyme component (PMID 40908429)
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