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Cold therapy causes vasoconstriction, reducing blood flow to the area and thereby decreasing inflammation, swelling, and pain
[11] [53] [54] [55] Evidence-based data from the literature are relatively limited, and some experts suggest that long-term phentermine pharmacotherapy for obesity does not induce abuse or psychological dependence (addiction), drug craving, and that abrupt treatment cessation within the normal prescription dose range does not induce amphetamine-like withdrawal
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Notably, current clinical guidelines do not recommend using PCOS phenotypes as a mandatory step in routine clinical decision-making, as subtype identification is not required for determining general management strategies [2]
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