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Rossing et al

Retrieved February 9, 2025

& Ladics, G

And those mechanisms, glucose-dependent insulin regulation, glucagon suppression, appetite modulation at the level of the brain, and direct effects on cardiovascular biology that appear independently of weight change, suggest that the obesity story, as dramatic as it has been, may ultimately prove to be the least interesting chapter in the GLP-1 narrative

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The regulatory and trial status of retatrutide may change