Regarding plasma B12 - this is not the case, serum B12 often remains highly elevated (well over the normal range) even while symptoms return - this is why testing B12 once treatment begins is not recommended
For many patients, medication is an excellent first step
It is important to note that although all exosomes are EVs, not all EVs are exosomes the defining feature of exosomes is their endosomal origin, which sets them apart from other EVs 210,211
doi: 10.1016/bs.vh.2022.01.010 13
Pearn ML, Niesman IR, Egawa J, Sawada A, Almenar-Queralt A, Shah SB, et al
For DME suppliers managing high volumes of enteral nutrition patients, practice management software that integrates documentation, billing, and compliance in one place reduces the manual reconciliation burden that creates most of the errors in the table above