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Using this model, we now demonstrate that Trkb deletion-induced iSPN dysfunction leads to a hyperdopaminergic state in the pre-symptomatic phase, before motor dysfunction onset, reminiscent of the dopaminergic dysfunction observed in the brains of patients with HD 3,4,5
Analysis of glutathione levels in the brain tissue samples from HIV-1-positive individuals and subject with Alzheimers disease and its implication in the pathophysiology of the disease process
This means the injection must be administered in an outpatient setting and associated with a qualifying diagnosis
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